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Antitumor activity

•Studies in mice and rats have shown that cannabinoids may inhibit tumor growth by causing cell death, blocking cell growth, and blocking the development of blood vessels needed by tumors to grow. Laboratory and animal studies have shown that cannabinoids may be able to kill cancer cells while protecting normal cells.

•A study in mice showed that cannabinoids may protect against inflammation of the colon and may have potential in reducing the risk of colon cancer, and possibly in its treatment.

•A laboratory study of delta-9-THC in hepatocellular carcinoma (liver cancer) cells showed that it damaged or killed the cancer cells. The same study of delta-9-THC in mouse models of liver cancer showed that it had antitumor effects. Delta-9-THC has been shown to cause these effects by acting on molecules that may also be found in non-small cell lung cancer cells and breast cancer cells.

•A laboratory study of cannabidiol in estrogen receptor positive and estrogen receptor negative breast cancer cells showed that it caused cancer cell death while having little effect on normal breast cells.

•A laboratory study of cannabidiol in human glioma cells showed that when given along with chemotherapy, cannabidiol may make chemotherapy more effective and increase cancer cell death without harming normal cells.

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Pain relief

•Cannabinoid receptors (molecules that bind cannabinoids) have been studied in the brain, spinal cord, and nerve endings throughout the body to understand their roles in pain relief.

•Cannabinoids have been studied for anti-inflammatory effects that may play a role in pain relief.

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Because Cannabis smoke contains many of the same substances as tobacco smoke, there are concerns about how smoked cannabis affects the lungs. A study of over 5,000 men and women without cancer over a period of 20 years found that smoking tobacco was linked with some loss of lung function but that occasional and low use of cannabis was not linked with loss of lung function.

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Because use of Cannabis over a long time may have harmful effects on the endocrine and reproductive systems, rates of testicular germ cell tumors (TGCTs) in Cannabis users have been studied. Larger studies that follow patients over time and laboratory studies of cannabinoid receptors in TGCTs are needed to find if there is a link between Cannabis use and a higher risk of TGCTs.

Both Cannabis and cannabinoids may be addictive.

Symptoms of withdrawal from cannabinoids may include:

•Irritability.

•Trouble sleeping.

•Restlessness.

•Hot flashes.

•Nausea and cramping (rarely occur).

These symptoms are mild compared to withdrawal from opiates and usually lessen after a few days.

Necifix

Nov 6 2013, 01:50 PM

Indeed, was it Thomas Jefferson who had the pot farm and he gave it away to everyone?

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Marijuana smoke contains a greater amount of carcinogens than tobacco smoke. In addition, marijuana users usually inhale more deeply and hold their breath longer than tobacco smokers do, further increasing the lungs exposure to carcinogenic smoke. Marijuana use is not only associated with adverse physical effects, but also mental, emotional and behavioral changes.

People who smoke marijuana frequently, but do not smoke tobacco, have more health problems and miss more days of work than nonsmokers. Many of these extra sick days are due to respiratory illnesses.

Patients considering using marijuana for medicinal purposes should make this decision in consultation with their doctor, and consider means of administration other than smoking.

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Lower Your Cholesterol

Alcohol also can have a very powerful effect and increase HDL "good" cholesterol by 20% if used moderately and in the context of a healthy diet along with regular physical activity, says Rimm. Higher HDL levels are linked to lower risks of heart disease.

"The research evidence points to ethanol, or the alcohol component, of beer, wine, or spirits as the substrate that can help lower cholesterol levels, increase 'good' HDL cholesterol," he says.

Boost Your Brain

A recent study shows a boost in brain power for women who enjoy a little alcohol. The study, published in the Jan. 20 issue of The New England Journal of Medicine, evaluated more than 12,000 women aged 70-81. Moderate drinkers scored better than teetotalers on tests of mental function. Researchers found a boost in brainpower with one drink a day. Moderate drinkers had a 23% reduced risk of mental decline compared with nondrinkers.